CCAR2 Antibody
Product Sizes
100 ul
£332.00
CSB-PA084028-100UL
About this Product
- SKU:
- CSB-PA084028
- Additional Names:
- CCAR2 antibody; DBC1 antibody; KIAA1967Cell cycle and apoptosis regulator protein 2 antibody; Cell division cycle and apoptosis regulator protein 2 antibody; DBIRD complex subunit KIAA1967 antibody; Deleted in breast cancer gene 1 protein antibody; DBC-1 antibody; DBC.1 antibody; NET35 antibody; p30 DBC antibody
- Application:
- ELISA, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis. Inhibits SUV39H1 methyltransferase activity. As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors. Plays a critical role in maintaining genomic stability and cellular integrity following UV-induced genotoxic stress. Nagase T., DNA Res. 8:319-327(2001). Hamaguchi M., Proc. Natl. Acad. Sci. U.S.A. 99:13647-13652(2002). Olsen J.V., Cell 127:635-648(2006).
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from internal of Human KIAA1967.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:CCAR2-Antibody-11085153.html
