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Antibodies

GRM3 Antibody

Product Sizes
50 ul
£186.00
CSB-PA074225-50UL
100 ul
£334.00
CSB-PA074225-100UL
About this Product
SKU:
CSB-PA074225
Additional Names:
GLUR3 antibody; Glutamate metabotropic receptor 3 antibody; Glutamate receptor metabotropic 3 antibody; GPRC1C antibody; GRM3 antibody; GRM3_HUMAN antibody; Metabotropic glutamate receptor 3 antibody; MGlu3 antibody; mGluR3 antibody
Application:
ELISA, Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Host:
Rabbit
Immunogen:
Synthetic peptide of Human GRM3
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody