IRF2 Antibody
Product Sizes
100 ul
£332.00
CSB-PA072893-100UL
About this Product
- SKU:
- CSB-PA072893
- Additional Names:
- DKFZp686F0244 antibody; Interferon regulatory factor 2 antibody; IRF 2 antibody; IRF-2 antibody; IRF2 antibody; IRF2_HUMAN antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation. Itoh S., Nucleic Acids Res. 17:8372-8372(1989). Cha Y., J. Biol. Chem. 269:5279-5287(1994). Staal A., J. Cell. Physiol. 185:269-279(2000).
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from internal of Human IRF2.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:IRF2-Antibody-11084861.html
