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Antibodies

IL4 Antibody

Product Sizes
50 ug
£186.00
CSB-PA06737A0RB-50UG
100 ug
£334.00
CSB-PA06737A0RB-100UG
About this Product
SKU:
CSB-PA06737A0RB
Additional Names:
B cell growth factor 1 antibody; B cell IgG differentiation factor antibody; B Cell Stimulatory Factor 1 antibody; B-cell stimulatory factor 1 antibody; BCGF 1 antibody; BCGF1 antibody; Binetrakin antibody; BSF-1 antibody; BSF1 antibody; IGG1 induction factor antibody; IL 4 antibody; IL-4 antibody; IL4 antibody; IL4_HUMAN antibody; Il4e12 antibody; Interleukin 4 antibody; Interleukin 4 variant 2 antibody; Interleukin 4; isoform 1 antibody; Interleukin-4 antibody; Lymphocyte stimulatory factor 1 antibody; MGC79402 antibody; Pitrakinra antibody
Application:
ELISA, Immunohistochemistry
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Clonality:
Polyclonal
Extra Details:
Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Genetic variations in IL4 may be a cause of susceptibility to ischemic stroke (ISCHSTR) [MIM:601367]; also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.
Host:
Rabbit
Immunogen:
Recombinant Human Interleukin-4 protein (25-153AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody
IHC image of CSB-PA06737A0Rb diluted at 1:300 and staining in paraffin-embedded human lymph node tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.