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Antibodies

RUNX1T1 Antibody

Product Sizes
50 ul
£186.00
CSB-PA066534-50UL
100 ul
£334.00
CSB-PA066534-100UL
About this Product
SKU:
CSB-PA066534
Additional Names:
Acute myelogenous leukemia 1 translocation 1 cyclin D related antibody; Acute myelogenous leukemia 1 translocation 1 protein antibody; AML1 MTG8 antibody; AML1T1 antibody; CBFA2T1 antibody; CDR antibody; Core binding factor runt domain alpha subunit 2 translocated to 1 antibody; Core binding factor runt domain alpha subunit 2 translocated to 1 cyclin D related antibody; Cyclin D related antibody; Cyclin D related protein antibody; Cyclin-D-related protein antibody; Eight twenty one protein antibody; ETO antibody; ETO protein antibody; MGC2796 antibody; MTG 8 antibody; MTG 8b antibody; MTG8 antibody; MTG8 protein antibody; MTG8_HUMAN antibody; MTG8b antibody; Myeloid translocation gene on 8q22 antibody; Protein CBFA2T1 antibody; Protein ETO antibody; Protein MTG 8 antibody; Protein MTG8 antibody; Runt related transcription factor 1 translocated to 1 (cyclin D related) antibody; Runt related transcription factor 1 translocated to 1 antibody; Runt related transcription factor 1 translocated to 1 cyclin D related antibody; RUNX1 translocation partner 1 antibody; RUNX1T1 antibody; Zinc finger MYND domain containing protein 2 antibody; Zinc finger MYND domain-containing protein 2 antibody; ZMYND 2 antibody; ZMYND2 antibody
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation.
Host:
Rabbit
Immunogen:
Synthetic peptide of Human RUNX1T1
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody