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Antibodies

IL12B Antibody

Product Sizes
50 ug
£186.00
CSB-PA06615A0RB-50UG
100 ug
£334.00
CSB-PA06615A0RB-100UG
About this Product
SKU:
CSB-PA06615A0RB
Additional Names:
CLMF antibody; CLMF p40 antibody; CLMF2 antibody; Cytotoxic lymphocyte maturation factor 40 kDa subunit antibody; IL 12B antibody; IL-12 subunit p40 antibody; IL-12B antibody; IL12 p40 antibody; IL12B antibody; IL12B_HUMAN antibody; IMD28 antibody; IMD29 antibody; Interleukin 12 beta chain antibody; Interleukin 12 p40 antibody; Interleukin-12 subunit beta antibody; NK cell stimulatory factor chain 2 antibody; NKSF antibody; NKSF2 antibody
Application:
ELISA, Immunohistochemistry, Western Blot
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Clonality:
Polyclonal
Extra Details:
Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Ref.12Associates with IL23A to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
Host:
Rabbit
Immunogen:
Recombinant Human Interleukin-12 subunit beta protein (23-328AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody