NEIL3 Antibody
Product Sizes
100 ul
£332.00
CSB-PA065468-100UL
About this Product
- SKU:
- CSB-PA065468
- Additional Names:
- 123 antibody; AI449477 antibody; BC034753 antibody; C85903 antibody; DNA glycosylase FPG2 antibody; DNA glycosylase hFPG2 antibody; DNA glycosylase/AP lyase Neil3 antibody; EC 3.2.2.- antibody; EC 4.2.99.18 antibody; Endonuclease 8-like 3 antibody; Endonuclease VIII-like 3 antibody; FGP2 antibody; FLJ10858 antibody; FPG2 antibody; hFPG2 antibody; hNEI3 antibody; MGC27861 antibody; MGC36916 antibody; Nei endonuclease VIII-like 3 (E. coli) antibody; nei endonuclease VIII-like 3 antibody; Nei like 3 (E. coli) antibody; Nei-like protein 3 antibody; NEI3 antibody; NEIL3 antibody; NEIL3_HUMAN antibody; OTTHUMP00000218810 antibody; RGD1310562 antibody
- Application:
- ELISA, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA; also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues. Seems to be an important facilitator of cell proliferation in certain populations, for example neural stem/progenitor cells and tumor cells, suggesting a role in replication-associated DNA repair. Takao M., J. Biol. Chem. 277:42205-42213(2002). Ota T., Nat. Genet. 36:40-45(2004). The MGC Project Team, Genome Res. 14:2121-2127(2004).
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from internal of Human NEIL3.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:NEIL3-Antibody-11085875.html
