TOP2A Antibody
Product Sizes
50 ul
£186.00
CSB-PA062296-50UL
100 ul
£334.00
CSB-PA062296-100UL
About this Product
- SKU:
- CSB-PA062296
- Additional Names:
- alpha isozyme antibody; ATP hydrolyzing DNA topoisomerase II alfa antibody; DNA gyrase antibody; DNA topoisomerase (ATP hydrolyzing) antibody; DNA topoisomerase 2 alpha antibody; DNA topoisomerase 2-alpha antibody; DNA topoisomerase II 170 kD antibody; DNA topoisomerase II alpha isozyme antibody; DNA topoisomerase II antibody; DNA Topoisomerase2 antibody; TOP 2A antibody; TOP2 antibody; TOP2A antibody; TOP2A_HUMAN antibody; Topoisomerase DNA II alpha 170kDa antibody; TP2A antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromosome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of Human TOP2A
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:TOP2A-Antibody-11103513.html
