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Antibodies

ACVR2A Antibody

Product Sizes
50 ul
£186.00
CSB-PA055681-50UL
100 ul
£334.00
CSB-PA055681-100UL
About this Product
SKU:
CSB-PA055681
Additional Names:
Activin A receptor type IIA antibody; Activin receptor type 2A antibody; Activin receptor type IIA antibody; Activin receptor type-2A antibody; ACTR 2 antibody; ACTR IIA antibody; ACTR-IIA antibody; ACTR2 antibody; ACTRII antibody; ACTRIIA antibody; Acvr 2 antibody; Acvr 2A antibody; Acvr2 antibody; ACVR2A antibody; AVR2A_HUMAN antibody; OTTHUMP00000197918 antibody
Application:
ELISA, Immunohistochemistry, Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.
Host:
Rabbit
Immunogen:
Synthetic peptide of Human ACVR2A
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody