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Antibodies

CERS4 Antibody

Product Sizes
50 ul
£186.00
CSB-PA054139-50UL
100 ul
£334.00
CSB-PA054139-100UL
About this Product
SKU:
CSB-PA054139
Additional Names:
ceramide synthase 4 antibody; CerS4 antibody; FLJ12089 antibody; LAG1 homolog ceramide synthase 4 antibody; LAG1 longevity assurance homolog 4 antibody; LAG1, S. cerevisiae, homolog of, 4 antibody; LASS 4 antibody; LASS4 antibody; LASS4 LAG1 homolog ceramide synthase 4 antibody; LASS4_HUMAN antibody; TRAM homolog 1 antibody; Trh 1 antibody; Trh1 antibody
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they are all involved in sphingolipid synthesis. LASS4 is a 394 amino acid endoplasmic reticulum, multi-pass membrane protein. LASS4 increases the levels of long ceramides such as C22:0- and C24:0-ceramides. In cells deficient for CLN9, as observed in neuronal ceroid lipofuscinosis (NCL) or Batten disease, LASS4 can increase ceramide levels and partially correct growth and apoptosis.
Host:
Rabbit
Immunogen:
Synthetic peptide of Human CERS4
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody