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Antibodies

DOCK1 Antibody

Product Sizes
100 ul
£332.00
CSB-PA047488-100UL
About this Product
SKU:
CSB-PA047488
Additional Names:
180 kDa protein downstream of CRK antibody; Ced5 antibody; Dedicator of Cytokinesis 1 antibody; Dedicator of cytokinesis protein 1 antibody; DOCK 1 antibody; DOCK 180 antibody; DOCK1 antibody; DOCK1_HUMAN antibody; DOCK180 antibody
Application:
ELISA, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Clonality:
Polyclonal
Extra Details:
Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1. Hasegawa H., Mol. Cell. Biol. 16:1770-1776(1996). Deloukas P., Nature 429:375-381(2004). Matsuda M., J. Biol. Chem. 271:14468-14472(1996).
Host:
Rabbit
Immunogen:
Synthesized peptide derived from internal of Human DOCK1.
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody