APAF1 Antibody

Product Sizes

50 ul

£186.00

CSB-PA043863-50UL

100 ul

£334.00

CSB-PA043863-100UL

About this Product

SKU:: CSB-PA043863
Additional Names:: APAF 1 antibody; Apaf-1 antibody; APAF_HUMAN antibody; Apaf1 antibody; Apoptotic peptidase activating factor 1 antibody; Apoptotic protease activating factor 1 antibody; Apoptotic protease activating factor antibody; Apoptotic protease-activating factor 1 antibody; CED 4 antibody; CED4 antibody; KIAA0413 antibody
Application:: ELISA, Immunohistochemistry, Western Blot
Buffer:: PBS
Clonality:: Polyclonal
Extra Details:: This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms.
Host:: Rabbit
Immunogen:: Synthetic peptide of Human APAF1
Isotype:: IgG
Physical State:: Liquid
Purification:: Affinity Purified
Reactivities:: Human, Mouse, Rat
Shipping Conditions:: Blue Ice
Storage Conditions:: -20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:: Cusabio
Type:: Antibody: Polyclonal Antibody

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