DIO2 Antibody
Product Sizes
50 ul
£186.00
CSB-PA033015-50UL
100 ul
£334.00
CSB-PA033015-100UL
About this Product
- SKU:
- CSB-PA033015
- Additional Names:
- 5DII antibody; D2 antibody; Deiodinase, iodothyronine, type II antibody; DIO2 antibody; DIOII antibody; EC 1.97.1.10 antibody; IOD2_HUMAN antibody; ITDI2 antibody; SelY antibody; Thyroxine deiodinase, type II antibody; TXDI2 antibody; Type 2 DI antibody; Type 2 iodothyronine deiodinase antibody; Type II 5' deiodinase antibody; Type II iodothyronine deiodinase antibody; Type-II 5''-deiodinase antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It is highly expressed in the thyroid, and may contribute significantly to the relative increase in thyroidal T3 production in patients with Graves disease and thyroid adenomas. This protein contains selenocysteine (Sec) residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of Human DIO2
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:DIO2-Antibody-11104633.html
