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Antibodies

FZD6 Antibody

Product Sizes
50 ul
£186.00
CSB-PA032335-50UL
100 ul
£334.00
CSB-PA032335-100UL
About this Product
SKU:
CSB-PA032335
Additional Names:
Frizzled 6 seven transmembrane spanning receptor antibody; Frizzled drosophila homolog of 6 antibody; Frizzled family receptor 6 antibody; Frizzled homolog 6 (Drosophila) antibody; Frizzled homolog 6 antibody; Frizzled-6 antibody; Frizzled6 antibody; Fz 6 antibody; Fz-6 antibody; Fz6 antibody; FZD 6 antibody; Fzd6 antibody; FZD6_HUMAN antibody; Hfz 6 antibody; hFz6 antibody; NDNC10 antibody
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.
Host:
Rabbit
Immunogen:
Synthetic peptide of Human FZD6
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human, Mouse
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody