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Antibodies

TJP1 Antibody

Product Sizes
50 ul
£186.00
CSB-PA023573HA01HU-50UL
100 ul
£334.00
CSB-PA023573HA01HU-100UL
About this Product
SKU:
CSB-PA023573HA01HU
Additional Names:
Tight junction protein 1 antibody; Tight junction protein ZO-1 antibody; Tight junction protein ZO1 antibody; TJP1 antibody; zo-1 antibody; Zo1 antibody; ZO1_HUMAN antibody; Zona occludens 1 antibody; Zona occludens 1 protein antibody; Zona occludens protein 1 antibody; Zonula occludens 1 protein antibody; Zonula occludens protein 1 antibody
Application:
ELISA, Immunofluorescence
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Clonality:
Polyclonal
Extra Details:
The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.
Immunogen:
Recombinant Human Tight junction protein ZO-1 protein (116-414aa)
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody
Immunofluorescence staining of U251 cells with CSB-PA023573HA01HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).