TDP1 Antibody
Product Sizes
50 ul
£186.00
CSB-PA023352ESR1HU-50UL
100 ul
£334.00
CSB-PA023352ESR1HU-100UL
About this Product
- SKU:
- CSB-PA023352ESR1HU
- Additional Names:
- AI838772 antibody; AW493413 antibody; FLJ11090 antibody; MGC104252 antibody; MGC112732 antibody; RP24-311F12.2 antibody; SCAN1 antibody; TDP1 antibody; TYDP antibody; TYDP1_HUMAN antibody; Tyr-DNA phosphodiesterase 1 antibody; Tyrosyl-DNA phosphodiesterase 1 antibody
- Application:
- ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue. Hydrolyzes 3'-phosphoglycolates on protruding 3' ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. Acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. Has low 3'exonuclease activity and can remove a single nucleoside from the 3'end of DNA and RNA molecules with 3'hydroxyl groups. Has no exonuclease activity towards DNA or RNA with a 3'phosphate.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Tyrosyl-DNA phosphodiesterase 1 protein (1-260AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:TDP1-Antibody-11081896.html
