Skip to content

Basket

You currently have no items in your basket.

Total (excl. vat) £0.00
View basket & checkout
Antibodies

PMEL Antibody

Product Sizes
50 ug
£186.00
CSB-PA021324LA01HU-50UG
100 ug
£334.00
CSB-PA021324LA01HU-100UG
About this Product
SKU:
CSB-PA021324LA01HU
Additional Names:
95 kDa melanocyte specific secreted glycoprotein antibody; 95 kDa melanocyte-specific secreted glycoprotein antibody; D12S53E antibody; gp100 antibody; M-beta antibody; ME20 antibody; ME20 M/ME20 S antibody; ME20-M antibody; ME20-S antibody; ME20M antibody; ME20M/ME20S antibody; ME20S antibody; Melanocyte lineage specific antigen GP100 antibody; Melanocyte protein mel 17 antibody; Melanocyte protein Pmel 17 antibody; Melanocyte protein Pmel 17 precursor antibody; Melanocytes lineage-specific antigen GP100 antibody; Melanoma associated ME20 antigen antibody; Melanoma gp100 antibody; Melanoma-associated ME20 antigen antibody; Melanosomal matrix protein 17 antibody; Melanosomal matrix protein17 antibody; P1 antibody; p100 antibody; p26 antibody; PMEL 17 antibody; PMEL antibody; PMEL_HUMAN antibody; PMEL17 antibody; Premelanosome protein antibody; Secreted melanoma-associated ME20 antigen antibody; SI antibody; SIL antibody; SILV antibody; Silver (mouse homolog) like antibody; Silver homolog antibody; Silver locus protein homolog antibody; Silver, mouse, homolog of antibody
Application:
ELISA, Immunohistochemistry, Western Blot
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Clonality:
Polyclonal
Extra Details:
Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.
Host:
Rabbit
Immunogen:
Recombinant Human Melanocyte protein PMEL protein (25-467AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody
Western blot All lanes: PMEL antibody at 14ug/ml + Jurkat whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 71, 61, 67 kDa Observed band size: 71 kDa
IHC image of CSB-PA021324LA01HU diluted at 1:200 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
IHC image of CSB-PA021324LA01HU diluted at 1:200 and staining in paraffin-embedded human melanoma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.