PVR Antibody
Product Sizes
50 ul
£186.00
CSB-PA019093ESR2HU-50UL
100 ul
£334.00
CSB-PA019093ESR2HU-100UL
About this Product
- SKU:
- CSB-PA019093ESR2HU
- Additional Names:
- CD155 antibody; CD155 antigen antibody; FLJ25946 antibody; HVED antibody; mE4 antibody; NECL 5 antibody; Necl-5 antibody; Necl5 antibody; Nectin like 5 antibody; Nectin like protein 5 antibody; Nectin-like protein 5 antibody; Ortholog of mouse Tage4 antibody; Poliovirus receptor antibody; PVR antibody; PVR_HUMAN antibody; PVS antibody; Taa1 antibody; Tage 4 antibody; TAGE4 antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytoxicity of activated NK cells. May also promote NK cell-target cell modular exchange, and PVR transfer to the NK cell. This transfer is more important in some tumor cells expressing a lot of PVR, and may trigger fratricide NK cell activation, providing tumors with a mechanism of immunoevasion. Plays a role in mediating tumor cell invasion and migration. Serves as a receptor for poliovirus attachment to target cells. May play a role in axonal transport of poliovirus, by targeting virion-PVR-containing endocytic vesicles to the microtubular network through interaction with DYNLT1. This interaction would drive the virus-containing vesicle to the axonal retrograde transport.2 Publications
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Poliovirus receptor protein (220-345AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:PVR-Antibody-11081936.html
