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Antibodies

PSMD4 Antibody

Product Sizes
50 ul
£186.00
CSB-PA018908HA01HU-50UL
100 ul
£334.00
CSB-PA018908HA01HU-100UL
About this Product
SKU:
CSB-PA018908HA01HU
Additional Names:
26S protease subunit S5a antibody; 26S proteasome non ATPase regulatory subunit 4 antibody; 26S proteasome non-ATPase regulatory subunit 4 antibody; 26S proteasome regulatory subunit rpn10 antibody; 26S proteasome regulatory subunit S5A antibody; AF 1 antibody; AF antibody; AF1 antibody; Angiocidin antibody; Antisecretory factor 1 antibody; ASF antibody; DS5a antibody; MCB 1 antibody; MCB1 antibody; Multiubiquitin chain binding protein antibody; Multiubiquitin chain-binding protein antibody; OTTHUMP00000059963 antibody; Prosome macropain antibody; Proteasome (prosome macropain) 26S subunit non ATPase 4 antibody; Proteasome 19S S5A antibody; Proteasome 26S non ATPase subunit 4 antibody; Proteasome 26S subunit non ATPase 4 antibody; PSMD 4 antibody; Psmd4 antibody; PSMD4_HUMAN antibody; pUB R5 antibody; pUBR5 antibody; Rpn 10 antibody; Rpn10 antibody; RPN10 homolog antibody; S5A antibody; S5a/antisecretory factor protein antibody
Application:
ELISA, Immunohistochemistry, Western Blot
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Clonality:
Polyclonal
Extra Details:
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMD4 acts as an ubiquitin receptor subunit through ubiquitin-interacting motifs and selects ubiquitin-conjugates for destruction. Displays a preferred selectivity for longer polyubiquitin chains.
Host:
Rabbit
Immunogen:
Recombinant Human 26S proteasome non-ATPase regulatory subunit 4 protein (161-377AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody
IHC image of CSB-PA018908HA01HU diluted at 1:100 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
IHC image of CSB-PA018908HA01HU diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Western Blot Positive WB detected in: HepG2 whole cell lysate, 293T whole cell lysate All lanes: PSMD4 antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 41, 29 kDa Observed band size: 41 kDa