PHF10 Antibody, FITC conjugated
Product Sizes
50 ug
£186.00
CSB-PA017898LC01HU-50UG
100 ug
£334.00
CSB-PA017898LC01HU-100UG
About this Product
- SKU:
- CSB-PA017898LC01HU
- Additional Names:
- BAF45a antibody; BRG1-associated factor 45a antibody; FLJ10975 antibody; MGC111009 antibody; PHD finger protein 10 antibody; PHD finger protein 10; isoform a antibody; PHD zinc finger protein XAP135 antibody; Phf10 antibody; PHF10_HUMAN antibody; XAP135 antibody
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Clonality:
- Polyclonal
- Conjugate:
- FITC
- Extra Details:
- Involved in transcription activity regulation by chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human PHD finger protein 10 protein (151-360AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:PHF10-AntibodyFITC-conjugated-11108379.html
