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Antibodies

PACS2 Antibody

Product Sizes
50 ug
£186.00
CSB-PA017372LA01HU-50UG
100 ug
£334.00
CSB-PA017372LA01HU-100UG
About this Product
SKU:
CSB-PA017372LA01HU
Additional Names:
6720425G15Rik antibody; AW208651 antibody; AW489976 antibody; E230011J22 antibody; FLJ25488 antibody; KIAA0602 antibody; mKIAA0602 antibody; PACS 2 antibody; PACS-2 antibody; PACS1 like protein antibody; PACS1-like protein antibody; PACS1L antibody; PACS2 antibody; PACS2_HUMAN antibody; Phosphofurin acidic cluster sorting protein 1 like antibody; Phosphofurin acidic cluster sorting protein 2 antibody
Application:
ELISA, Immunohistochemistry
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Clonality:
Polyclonal
Extra Details:
Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.
Host:
Rabbit
Immunogen:
Recombinant Human Phosphofurin acidic cluster sorting protein 2 protein (268-465AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody
IHC image of CSB-PA017372LA01HU diluted at 1:400 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
IHC image of CSB-PA017372LA01HU diluted at 1:400 and staining in paraffin-embedded human melanoma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.