OSBP Antibody, Biotin conjugated
Product Sizes
50 ul
£186.00
CSB-PA017254LD01HU-50UL
100 ul
£334.00
CSB-PA017254LD01HU-100UL
About this Product
- SKU:
- CSB-PA017254LD01HU
- Additional Names:
- OSBP 1 antibody; OSBP antibody; OSBP1_HUMAN antibody; Oxysterol binding protein 1 antibody; Oxysterol-binding protein 1 antibody
- Application:
- ELISA
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Clonality:
- Polyclonal
- Conjugate:
- Biotin
- Extra Details:
- Lipid transporter involved in lipid countertransport between the Golgi complex and membranes of the endoplasmic reticulum: specifically exchanges sterol with phosphatidylinositol 4-phosphate (PI4P), delivering sterol to the Golgi in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum (PubMed:24209621). Binds cholesterol and a range of oxysterols including 25-hydroxycholesterol (PubMed:15746430, PubMed:17428193). Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylates ERK1/2, whereas 25-hydroxycholesterol causes its disassembly (PubMed:15746430). Regulates cholesterol efflux by decreasing ABCA1 stability (PubMed:18450749).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Oxysterol-binding protein 1 protein (628-802AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:OSBP-Antibody--Biotin-conjugated-12923825.html
