MCM2 Antibody
Product Sizes
100 ul
£332.00
CSB-PA016903-100UL
About this Product
- SKU:
- CSB-PA016903
- Additional Names:
- BM28 antibody; CCNL 1 antibody; CCNL1 antibody; CDC like 1 antibody; cdc19 antibody; CDCL 1 antibody; CDCL1 antibody; Cell devision cycle like 1 antibody; Cyclin like 1 antibody; D3S3194 antibody; DNA replication licensing factor MCM2 antibody; KIAA0030 antibody; MCM 2 antibody; MCM2 antibody; MCM2 minichromosome maintenance deficient 2 mitotin antibody; MCM2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae) antibody; MCM2 minichromosome maintenance deficient 2; mitotin antibody; MCM2_HUMAN antibody; MGC10606 antibody; Minichromosome maintenance complex component 2 antibody; Minichromosome maintenance deficient 2 (mitotin) antibody; Minichromosome maintenance deficient 2 mitotin antibody; Minichromosome maintenance protein 2 antibody; Minichromosome maintenance protein 2 homolog antibody; Mitotin antibody; Nuclear protein BM28 antibody; OTTHUMP00000216047 antibody; OTTHUMP00000216050 antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Clonality:
- Polyclonal
- Extra Details:
- Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division. H Yan, Genes & Dev., Jun 1991; 5: 944 - 957. Yukio Ishimi, J. Biol. Chem., Nov 2001; 276: 42744 - 42752. Muluye E. Liku, Mol. Biol. Cell, Oct 2005; 16: 5026 - 5039. Daniela S. Dimitrova, J. Cell Biol., Aug 1999; 146: 709.
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from Human MCM2.
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:MCM2-Antibody-11084605.html
