OLR1 Antibody, FITC conjugated
Product Sizes
50 ug
£186.00
CSB-PA016331LC01HU-50UG
100 ug
£334.00
CSB-PA016331LC01HU-100UG
About this Product
- SKU:
- CSB-PA016331LC01HU
- Additional Names:
- C-type lectin domain family 8 member A antibody; CLEC8A antibody; hLOX 1 antibody; hLOX-1 antibody; Lectin like oxidized LDL receptor 1 antibody; Lectin like oxLDL receptor 1 antibody; Lectin type oxidized LDL receptor 1 antibody; Lectin-like oxidized LDL receptor 1 antibody; Lectin-like oxLDL receptor 1 antibody; Lectin-type oxidized LDL receptor 1 antibody; low density lipoprotein oxidized, receptor 1 antibody; LOX-1 antibody; LOXIN antibody; Olr1 antibody; OLR1_HUMAN antibody; Ox LDL receptor 1 antibody; Ox-LDL receptor 1 antibody; Oxidised low density lipoprotein (lectin like) receptor 1 antibody; Oxidized low density lipoprotein receptor 1 antibody; Oxidized low density lipoprotein receptor 1 soluble form antibody; Oxidized low-density lipoprotein receptor 1 antibody; OxLDL receptor 1 antibody; SCARE1 antibody; Scavenger receptor class E, member 1 antibody; SLOX1 antibody; soluble form antibody; SR-EI antibody
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Clonality:
- Polyclonal
- Conjugate:
- FITC
- Extra Details:
- Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Oxidized low-density lipoprotein receptor 1 protein (58-273AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:OLR1-AntibodyFITC-conjugated-1042085.html
