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Antibodies

NR2C2 Antibody

Product Sizes
50 ul
£186.00
CSB-PA016052ESR1HU-50UL
100 ul
£334.00
CSB-PA016052ESR1HU-100UL
About this Product
SKU:
CSB-PA016052ESR1HU
Additional Names:
hTAK1 antibody; Nr2c2 antibody; NR2C2_HUMAN antibody; Nuclear hormone receptor TR4 antibody; Nuclear receptor subfamily 2 group C member 2 antibody; Orphan nuclear receptor TAK1 antibody; Orphan nuclear receptor TR4 antibody; TAK1 antibody; Testicular nuclear receptor 4 antibody; Testicular receptor 4 antibody; TR2R1 antibody; TR4 antibody; TR4 nuclear hormone receptor antibody
Application:
ELISA, Immunohistochemistry
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
Orphan nuclear receptor that can act as a repressor or activator of transcription. An important repressor of nuclear receptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways. May regulate gene expression during the late phase of spermatogenesis. Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Plays a fundamental role in early embryonic development and embryonic stem cells. Required for normal spermatogenesis and cerebellum development. Appears to be important for neurodevelopmentally regulated behavior (By similarity). Activates transcriptional activity of LHCG. Antagonist of PPARA-mediated transactivation.
Host:
Rabbit
Immunogen:
Recombinant Human Nuclear receptor subfamily 2 group C member 2 protein (240-380AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody