NDP Antibody, FITC conjugated
Product Sizes
50 ug
£186.00
CSB-PA015609LC01HU-50UG
100 ug
£334.00
CSB-PA015609LC01HU-100UG
About this Product
- SKU:
- CSB-PA015609LC01HU
- Additional Names:
- EVR2 antibody; Exudative vitreoretinopathy 2 (X linked) antibody; FEVR antibody; ND antibody; NDP antibody; NDP_HUMAN antibody; Norrie disease (pseudoglioma) antibody; Norrie disease protein antibody; Norrin antibody; Norrin precursor antibody; X linked exudative vitreoretinopathy 2 protein antibody; X-linked exudative vitreoretinopathy 2 protein antibody
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Clonality:
- Polyclonal
- Conjugate:
- FITC
- Extra Details:
- Activates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. Plays a central role in retinal vascularization by acting as a ligand for FZD4 that signals via stabilizing beta-catenin (CTNNB1) and activating LEF/TCF-mediated transcriptional programs. Acts in concert with TSPAN12 to activate FZD4 independently of the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1). May be involved in a pathway that regulates neural cell differentiation and proliferation. Possible role in neuroectodermal cell-cell interaction.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Norrin protein (25-133AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:NDP-Antibody-FITC-conjugated-12781090.html
