MOCS3 Antibody
Product Sizes
50 ul
£186.00
CSB-PA014707ESR2HU-50UL
100 ul
£334.00
CSB-PA014707ESR2HU-100UL
About this Product
- SKU:
- CSB-PA014707ESR2HU
- Additional Names:
- Adenylyltransferase MOCS3 antibody; dJ914P20.3 antibody; MGC9252 antibody; MOCS 3 antibody; MOCS3 antibody; MOCS3_HUMAN antibody; Molybdenum cofactor synthesis 3 antibody; Molybdenum cofactor synthesis protein 3 antibody; Molybdopterin synthase sulfurylase antibody; Molybdopterin-synthase sulfurtransferase antibody; MPT synthase sulfurylase antibody; Sulfur carrier protein MOCS2A adenylyltransferase antibody; Sulfur carrier protein MOCS2A sulfurtransferase antibody; Sulfurtransferase MOCS3 antibody; UBA 4 antibody; UBA4 ubiquitin activating enzyme E1 homolog antibody; UBA4 antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Adenylyltransferase and sulfurtransferase MOCS3 protein (271-460AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:MOCS3-Antibody-11909150.html
