MLF1 Antibody

Product Sizes

50 ul

£186.00

CSB-PA014621ESR1HU-50UL

100 ul

£334.00

CSB-PA014621ESR1HU-100UL

About this Product

SKU:: CSB-PA014621ESR1HU
Additional Names:: Hls7 antibody; MLF1 antibody; MLF1_HUMAN antibody; Myelodysplasia myeloid leukemia factor 1 antibody; Myelodysplasia-myeloid leukemia factor 1 antibody; Myeloid leukemia factor 1 antibody; myeloid leukemia factor 1 variant 1 antibody; myeloid leukemia factor 1 variant 2 antibody; myeloid leukemia factor 1 variant 3 antibody
Application:: ELISA, Immunohistochemistry, Western Blot
Buffer:: PBS
Clonality:: Polyclonal
Extra Details:: Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
Host:: Rabbit
Immunogen:: Recombinant Human Myeloid leukemia factor 1 protein (1-268AA)
Isotype:: IgG
Physical State:: Liquid
Purification:: Affinity Purified
Reactivities:: Human, Mouse
Shipping Conditions:: Blue Ice
Storage Conditions:: -20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:: Cusabio
Type:: Antibody: Polyclonal Antibody

Basket