MEOX1 Antibody
Product Sizes
50 ul
£186.00
CSB-PA013695ESR2HU-50UL
100 ul
£334.00
CSB-PA013695ESR2HU-100UL
About this Product
- SKU:
- CSB-PA013695ESR2HU
- Additional Names:
- Homeobox protein MOX-1 antibody; MEOX1 antibody; MEOX1_HUMAN antibody; Mesenchyme homeo box 1 antibody; Mesenchyme homeobox 1 antibody; MOX 1 antibody; MOX1 antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- Mesodermal transcription factor that plays a key role in somitogenesis and is specifically required for sclerotome development. Required for maintenance of the sclerotome polarity and formation of the cranio-cervical joints (PubMed:23290072, PubMed:24073994). Binds specifically to the promoter of target genes and regulates their expression. Activates expression of NKX3-2 in the sclerotome. Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner. Required for hematopoietic stem cell (HSCs) induction via its role in somitogenesis: specification of HSCs occurs via the deployment of a specific endothelial precursor population, which arises within a sub-compartment of the somite named endotome.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Homeobox protein MOX-1 protein (1-254AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:MEOX1-Antibody-11909148.html
