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Antibodies

MASP1 Antibody, FITC conjugated

Product Sizes
50 ug
£186.00
CSB-PA013508LC01HU-50UG
100 ug
£334.00
CSB-PA013508LC01HU-100UG
About this Product
SKU:
CSB-PA013508LC01HU
Additional Names:
MASP1 antibody; CRARF antibody; CRARF1 antibody; PRSS5Mannan-binding lectin serine protease 1 antibody; EC 3.4.21.- antibody; Complement factor MASP-3 antibody; Complement-activating component of Ra-reactive factor antibody; Mannose-binding lectin-associated serine protease 1 antibody; MASP-1 antibody; Mannose-binding protein-associated serine protease antibody; Ra-reactive factor serine protease p100 antibody; RaRF antibody; Serine protease 5) [Cleaved into: Mannan-binding lectin serine protease 1 heavy chain; Mannan-binding lectin serine protease 1 light chain] antibody
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Clonality:
Polyclonal
Conjugate:
FITC
Extra Details:
Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5.
Host:
Rabbit
Immunogen:
Recombinant Human Mannan-binding lectin serine protease 1 protein (20-699AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody