KLRK1 Antibody, Biotin conjugated
Product Sizes
50 ug
£186.00
CSB-PA012474LD01HU-50UG
100 ug
£334.00
CSB-PA012474LD01HU-100UG
About this Product
- SKU:
- CSB-PA012474LD01HU
- Additional Names:
- CD314 antibody; CD314 antigen antibody; D12S2489E antibody; Killer cell lectin like receptor subfamily K member 1 antibody; Killer cell lectin-like receptor subfamily K member 1 antibody; KLR antibody; KLRC4 KLRK1 readthrough antibody; KLRK1 antibody; NK cell receptor D antibody; NK lectin-like receptor antibody; NKG2 D activating NK receptor antibody; NKG2 D type II integral membrane protein antibody; NKG2-D antibody; NKG2-D type II integral membrane protein antibody; NKG2-D-activating NK receptor antibody; Nkg2d antibody; NKG2D_HUMAN antibody; NKLLR antibody; NKR P2 antibody; Nkrp2 antibody
- Application:
- ELISA
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Clonality:
- Polyclonal
- Conjugate:
- Biotin
- Extra Details:
- Function as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF-alpha. Participates in NK cell-mediated bone marrow graft rejection. May play a regulatory role in differentiation and survival of NK cells. Binds to ligands belonging to various subfamilies of MHC class I-related glycoproteins including MICA, MICB, RAET1E, RAET1G, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human NKG2-D type II integral membrane protein (73-216AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:KLRK1-AntibodyBiotin-conjugated-12550511.html
