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Antibodies

KEAP1 Antibody, Biotin conjugated

Product Sizes
50 ug
£186.00
CSB-PA012147LD01HU-50UG
100 ug
£334.00
CSB-PA012147LD01HU-100UG
About this Product
SKU:
CSB-PA012147LD01HU
Additional Names:
Cytosolic inhibitor of Nrf2 antibody; INrf 2 antibody; INrf2 antibody; Keap 1 antibody; KEAP1 antibody; KEAP1_HUMAN antibody; Kelch like ECH associated protein 1 antibody; Kelch like family member 19 antibody; Kelch like protein 19 antibody; Kelch-like ECH-associated protein 1 antibody; Kelch-like protein 19 antibody; KIAA0132 antibody; KLHL 19 antibody; KLHL19 antibody; MGC10630 antibody; MGC1114 antibody; MGC20887 antibody; MGC4407 antibody; MGC9454 antibody
Application:
ELISA
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Clonality:
Polyclonal
Conjugate:
Biotin
Extra Details:
Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
Host:
Rabbit
Immunogen:
Recombinant Human Kelch-like ECH-associated protein 1 protein (1-624AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody