ITGB7 Antibody
Product Sizes
50 ul
£186.00
CSB-PA011891ESR2HU-50UL
100 ul
£334.00
CSB-PA011891ESR2HU-100UL
About this Product
- SKU:
- CSB-PA011891ESR2HU
- Additional Names:
- Gut homing receptor beta subunit antibody; Integrin beta 7 subunit antibody; Integrin beta-7 antibody; Integrin beta-P antibody; Integrin; beta 7 antibody; ITB7 antibody; ITB7_HUMAN antibody; Itgb7 antibody; Ly69 antibody; M290 IEL antigen antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT). Integrin alpha-4/beta-7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract. Interacts also with VCAM1 and fibronectin, an extracellular matrix component. It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Interactions involves the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin. Binds to HIV-1 gp120, thereby allowing the virus to enter GALT, which is thought to be the major trigger of AIDS disease. Interaction would involve a tripeptide L-D-I in HIV-1 gp120. Integrin alpha-E/beta-7 (HML-1) is a receptor for E-cadherin.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Integrin beta-7 protein (1-140AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:ITGB7-Antibody-11909860.html
