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Antibodies

ITGB2 Antibody

Product Sizes
50 ug
£186.00
CSB-PA011884LA01HU-50UG
100 ug
£334.00
CSB-PA011884LA01HU-100UG
About this Product
SKU:
CSB-PA011884LA01HU
Additional Names:
95 subunit beta antibody; Beta 2 (antigen CD18 (p95) antibody; CD 18 antibody; CD18 antibody; Cell surface adhesion glycoprotein LFA 1/CR3/P150,959 beta subunit precursor) antibody; Cell surface adhesion glycoproteins LFA 1/CR3/p150,95 subunit beta antibody; Cell surface adhesion glycoproteins LFA-1/CR3/p150 antibody; Complement component 3 receptor 3 and 4 subunit antibody; Complement receptor C3 beta subunit antibody; Complement receptor C3 subunit beta antibody; Integrin beta 2 antibody; Integrin beta chain beta 2 antibody; Integrin beta-2 (ITGB2) antibody; Integrin beta-2 antibody; Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) antibody; ITB2_HUMAN antibody; ITGB2 antibody; LAD antibody; LCAMB antibody; Leukocyte associated antigens CD18/11A, CD18/11B, CD18/11C antibody; Leukocyte cell adhesion molecule CD18 antibody; LFA 1 antibody; LFA1 antibody; Lymphocyte function associated antigen 1 (LFA1) antibody; Lymphocyte function associated antigen 1 antibody; MAC 1 antibody; MAC1 antibody; Macrophage antigen 1 (mac1) beta antibody; MF17 antibody; MFI7 antibody; OTTHUMP00000115278 antibody; OTTHUMP00000115279 antibody; OTTHUMP00000115280 antibody; OTTHUMP00000115281 antibody; OTTHUMP00000115282 antibody
Application:
ELISA, Immunofluorescence, Immunohistochemistry
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Clonality:
Polyclonal
Extra Details:
Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. Contributes to natural killer cell cytotoxicity (PubMed:15356110). Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils (PubMed:11812992). Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation (PubMed:18587400). Integrin alpha-L/beta-2 in assosiation with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed:23775590).
Host:
Rabbit
Immunogen:
Recombinant Human Integrin beta-2 protein (37-201AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody