IRF8 Antibody
Product Sizes
50 ul
£186.00
CSB-PA011823ESR1HU-50UL
100 ul
£334.00
CSB-PA011823ESR1HU-100UL
About this Product
- SKU:
- CSB-PA011823ESR1HU
- Additional Names:
- H ICSBP antibody; H-ICSBP antibody; HGNC:5358 antibody; HICSBP antibody; ICSBP 1 antibody; ICSBP antibody; ICSBP1 antibody; Interferon consensus sequence binding protein 1 antibody; Interferon consensus sequence binding protein antibody; Interferon consensus sequence-binding protein antibody; Interferon regulatory factor 8 antibody; IRF 8 antibody; IRF-8 antibody; Irf8 antibody; IRF8_HUMAN antibody; MYLS antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a negative regulatory role in cells of the immune system. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF8 and activation of genes.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Interferon regulatory factor 8 protein (137-426AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:IRF8-Antibody-1091911.html
