IL7 Antibody
Product Sizes
100 ul
£445.00
CSB-PA011669KA01HU-100UL
About this Product
- SKU:
- CSB-PA011669KA01HU
- Additional Names:
- IL 7 antibody; IL-7 antibody; Il7 antibody; IL7_HUMAN antibody; Interleukin 7 antibody; Interleukin-7 antibody; LP-1 antibody; Lymphopoietin 1 antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- Store at -20°C or -80°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- Clonality:
- Polyclonal
- Extra Details:
- IL-7 plays a key role in lymphopoiesis and lymphoid homeostasis. Stromal and epithelial cells within the bone marrow and thymus produce IL-7. The primary targets of IL-7 are T cells, B cells, and dendritic cells. IL-7 is crucial for T cell development, the importance of which is underscored by the lack of T cells in both mice and humans that are deficient in IL-7/IL-7R signaling. While IL-7 appears to be required for B cell development in mice, the role of IL-7 in human B cell development is unclear. In addition to its effects on T cell lymphopoiesis, IL-7 promotes the maintenance and survival of naive and memory A AlphaB Beta T cells, as well as G GammaD Delta T cells. The IL-7 receptor is a heterodimer of the common G Gamma chain, G Gammac, and the IL-7-specific IL-7RA Alpha. IL-7 activates PI3K/Akt, Jak1/2, and Stat1, 3, and 5.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of Human IL7
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:IL7-Antibody-158089.html
