IL10 Antibody
Product Sizes
100 ul
£445.00
CSB-PA011580KA01HU-100UL
About this Product
- SKU:
- CSB-PA011580KA01HU
- Additional Names:
- CSIF antibody; Cytokine synthesis inhibitory factor antibody; GVHDS antibody; IL 10 antibody; IL-10 antibody; IL10 antibody; IL10_HUMAN antibody; IL10A antibody; Interleukin 10 antibody; Interleukin-10 antibody; MGC126450 antibody; MGC126451 antibody; T-cell growth inhibitory factor antibody; TGIF antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- Store at -20°C or -80°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- Clonality:
- Polyclonal
- Extra Details:
- IL-10 is an anti-inflammatory cytokine that is produced by T cells, NK cells and macrophages. IL-10 initiates signal transduction by binding to a cell surface receptor complex consisting of IL-10 RI and IL-10 RII. Binding of IL-10 leads to the activation of Jak1 and Tyk2, which phosphorylates Stat-3. The anti-inflammatory activity of IL-10 is due to its ability to block signaling through other cytokine receptors, notably IFNG Gamma receptor, by upregulating expression of SOCS-1. In addition, IL-10 promotes T cell tolerance by inhibiting tyrosine phosphorylation of CD28. IL-10 is an important negative regulator of the immune response, which allows for maintenance of pregnancy. In contrast, increased IL-10 levels contribute to persistent Leishmania major infections.
- Host:
- Rabbit
- Immunogen:
- Recombinant protein of Human IL10
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human, Mouse, Rat
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:IL10-Antibody-158193.html
