IGHD Antibody
Product Sizes
50 ug
£186.00
CSB-PA011113LA01HU-50UG
100 ug
£334.00
CSB-PA011113LA01HU-100UG
About this Product
- SKU:
- CSB-PA011113LA01HU
- Additional Names:
- IGHD antibody; Immunoglobulin heavy constant delta antibody; Ig delta chain C region antibody; Ig delta chain C region NIG-65 antibody; Ig delta chain C region WAH antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Clonality:
- Polyclonal
- Extra Details:
- IgD is the major antigen receptor isotype on the surface of most peripheral B-cells, where it is coexpressed with IgM. The membrane-bound IgD (mIgD) induces the phosphorylation of CD79A and CD79B by the Src family of protein tyrosine kinases. Soluble IgD (sIgD) concentration in serum below those of IgG, IgA, and IgM but much higher than that of IgE. IgM and IgD molecules present on B cells have identical V regions and antigen-binding sites. After the antigen binds to the B-cell receptor, the secreted form sIgD is shut off. IgD is a potent inducer of TNF, IL1B, and IL1RN. IgD also induces release of IL6, IL10, and LIF from peripheral blood mononuclear cells. Monocytes seem to be the main producers of cytokines in vitro in the presence of IgD.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Ig delta chain C region protein (1-240AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Secondary Antibodies
- Manufacturer's Data Sheet:IGHD-Antibody-12553606.html
