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Antibodies

IGHA2 Antibody, FITC conjugated

Product Sizes
50 ug
£186.00
CSB-PA011112LC01HU-50UG
100 ug
£334.00
CSB-PA011112LC01HU-100UG
About this Product
SKU:
CSB-PA011112LC01HU
Additional Names:
IGHA2Immunoglobulin heavy constant alpha 2 antibody; Ig alpha-2 chain C region antibody; Ig alpha-2 chain C region BUT antibody; Ig alpha-2 chain C region LAN antibody
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Clonality:
Polyclonal
Conjugate:
FITC
Extra Details:
Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268). Ig alpha is the major immunoglobulin class in body secretions (PubMed:2241915).
Host:
Rabbit
Immunogen:
Recombinant Human Immunoglobulin heavy constant alpha 2 protein (36-111AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Secondary Antibodies