HTR2B Antibody
Product Sizes
50 ul
£186.00
CSB-PA010888ESR1HU-50UL
100 ul
£334.00
CSB-PA010888ESR1HU-100UL
About this Product
- SKU:
- CSB-PA010888ESR1HU
- Additional Names:
- 5 HT 2B antibody; 5 HT 2B receptor antibody; 5 HT(2B) antibody; 5 HT2B antibody; 5 hydroxytryptamine (serotonin) receptor 2B antibody; 5 hydroxytryptamine (serotonin) receptor 2B G protein coupled antibody; 5 hydroxytryptamine 2B receptor antibody; 5 hydroxytryptamine receptor 2B antibody; 5-HT-2B antibody; 5-HT2B antibody; 5-hydroxytryptamine receptor 2B antibody; 5HT(2B) antibody; 5HT2B Receptor antibody; 5HT2B_HUMAN antibody; 5HT2F antibody; Htr 2b antibody; Htr2b antibody; NP75 protein antibody; SEROTONIN 5HT2B RECEPTOR antibody; Serotonin receptor 2B antibody; Stomach fundus serotonin receptor antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca2+ ions from intracellular stores. Plays a role in the regulation of dopamine and 5-hydroxytryptamine release, 5-hydroxytryptamine uptake and in the regulation of extracellular dopamine and 5-hydroxytryptamine levels, and thereby affects neural activity. May play a role in the perception of pain. Plays a role in the regulation of behavior, including impulsive behavior. Required for normal proliferation of embryonic cardiac myocytes and normal heart development. Protects cardiomyocytes against apoptosis. Plays a role in the adaptation of pulmonary arteries to chronic hypoxia. Plays a role in vasoconstriction. Required for normal osteoblast function and proliferation, and for maintaining normal bone density. Required for normal proliferation of the interstitial cells of Cajal in the intestine.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human 5-hydroxytryptamine receptor 2B protein (382-481AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:HTR2B-Antibody-11080939.html
