LAMTOR5 Antibody
Product Sizes
50 ul
£186.00
CSB-PA010161ESR1HU-50UL
100 ul
£334.00
CSB-PA010161ESR1HU-100UL
About this Product
- SKU:
- CSB-PA010161ESR1HU
- Additional Names:
- HBV X interacting protein antibody; HBV X-interacting protein antibody; HBX interacting protein antibody; HBX-interacting protein antibody; hbxip antibody; HBXIP_HUMAN antibody; Hepatitis B virus X interacting protein antibody; Hepatitis B virus X-interacting protein antibody; LAMTOR5 antibody; Late endosomal/lysosomal adaptor MAPK and MTOR activator 5 antibody; MGC71071 antibody; Ragulator complex protein LAMTOR5 antibody; XIP antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. When complexed to BIRC5, interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway. Down-regulates hepatitis B virus (HBV) replication.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Ragulator complex protein LAMTOR5 protein (1-91AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:LAMTOR5-Antibody-11908713.html
