GLRA1 Antibody, HRP conjugated
Product Sizes
50 ug
£186.00
CSB-PA009516LB01HU-50UG
100 ug
£334.00
CSB-PA009516LB01HU-100UG
About this Product
- SKU:
- CSB-PA009516LB01HU
- Additional Names:
- GLRA1 antibody; GLRA1_HUMAN antibody; Glycine receptor 48 kDa subunit antibody; Glycine receptor alpha 1 antibody; Glycine receptor strychnine-binding subunit antibody; Glycine receptor subunit alpha-1 antibody; Glycine receptor; alpha 1 subunit antibody; HKPX1 antibody; STHE antibody
- Application:
- ELISA
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Clonality:
- Polyclonal
- Conjugate:
- HRP
- Extra Details:
- Glycine receptors are ligand-gated chloride channels (PubMed:23994010, PubMed:25730860). Channel opening is triggered by extracellular glycine (PubMed:2155780, PubMed:7920629, PubMed:14551753, PubMed:16144831, PubMed:22715885, PubMed:22973015, PubMed:25973519, PubMed:9009272). Channel opening is also triggered by taurine and beta-alanine (PubMed:16144831, PubMed:9009272). Channel characteristics depend on the subunit composition; heteropentameric channels are activated by lower glycine levels and display faster desensitization (PubMed:14551753). Plays an important role in the down-regulation of neuronal excitability (PubMed:8298642, PubMed:9009272). Contributes to the generation of inhibitory postsynaptic currents (PubMed:25445488). Channel activity is potentiated by ethanol (PubMed:25973519). Potentiation of channel activity by intoxicating levels ot ethanol contribute to the sedative effects of ethanol (By similarity).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Glycine receptor subunit alpha-1 protein (23-113AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:GLRA1-AntibodyHRP-conjugated-12553535.html
