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Antibodies

FKBP4 Antibody

Product Sizes
50 ug
£186.00
CSB-PA008700EA01HU-50UG
100 ug
£334.00
CSB-PA008700EA01HU-100UG
About this Product
SKU:
CSB-PA008700EA01HU
Additional Names:
51 kDa FK506-binding protein antibody; 52 kDa FK506 binding protein antibody; 52 kDa FK506-binding protein antibody; 52 kDa FKBP antibody; 59 kDa immunophilin antibody; FK506 binding protein 4 antibody; FK506-binding protein 4 antibody; FKBP 4 antibody; FKBP 52 antibody; FKBP 59 antibody; FKBP-4 antibody; FKBP-52 antibody; FKBP4 antibody; FKBP4_HUMAN antibody; FKBP51 antibody; FKBP52 protein antibody; FKBP59 antibody; HBI antibody; Hsp 56 antibody; HSP binding immunophilin antibody; HSP-binding immunophilin antibody; Hsp56 antibody; Immunophilin FKBP52 antibody; N-terminally processed antibody; p52 antibody; p59 antibody; p59 protein antibody; Peptidyl prolyl cis trans isomerase antibody; peptidyl-prolyl cis-trans isomerase antibody; Peptidyl-prolyl cis-trans isomerase FKBP4 antibody; Peptidylprolyl cis trans isomerase antibody; PPIase antibody; PPIase FKBP4 antibody; Rotamase antibody; T cell FK506 binding protein 59kD antibody
Application:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Buffer:
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Clonality:
Polyclonal
Extra Details:
Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria.
Host:
Rabbit
Immunogen:
Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP4 protein (1-240AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Protein G Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody
Immunofluorescence staining of Hela cells with CSB-PA008700EA01HU at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
IHC image of CSB-PA008700EA01HU diluted at 1:400 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
IHC image of CSB-PA008700EA01HU diluted at 1:400 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Western Blot Positive WB detected in: Hela whole cell lysate, Jurkat whole cell lysate, PC-3 whole cell lysate, MCF-7 whole cell lysate, K562 whole cell lysate, HepG2 whole cell lysate, 293T whole cell lysate All lanes: FKBP4 antibody at 3.3ug/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 52 kDa Observed band size: 59 kDa