FEN1 Antibody, Biotin conjugated
Product Sizes
50 ul
£186.00
CSB-PA008585LD01DOA-50UL
100 ul
£334.00
CSB-PA008585LD01DOA-100UL
About this Product
- SKU:
- CSB-PA008585LD01DOA
- Additional Names:
- FEN1 antibody; At5g26680 antibody; F21E10.3Flap endonuclease 1 antibody; FEN-1 antibody; EC 3.1.-.- antibody; Flap structure-specific endonuclease 1 antibody
- Application:
- ELISA
- Buffer:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
- Clonality:
- Polyclonal
- Conjugate:
- Biotin
- Extra Details:
- Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinicapyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
- Host:
- Rabbit
- Immunogen:
- Recombinant Arabidopsis thaliana Flap endonuclease 1 protein (85-383AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Protein G Purified
- Reactivities:
- Plant
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:FEN1-Antibody--Biotin-conjugated-12926462.html
