ERLIN2 Antibody
Product Sizes
50 ul
£186.00
CSB-PA007791ESR2HU-50UL
100 ul
£334.00
CSB-PA007791ESR2HU-100UL
About this Product
- SKU:
- CSB-PA007791ESR2HU
- Additional Names:
- C8orf2 antibody; Chromosome 8 open reading frame 2 antibody; Endoplasmic reticulum lipid raft associated protein 2 antibody; Endoplasmic reticulum lipid raft-associated protein 2 antibody; ER lipid raft associated 2 antibody; ERLIN 2 antibody; Erlin-2 antibody; ERLIN2 antibody; ERLN2_HUMAN antibody; HGNC:1356 antibody; MGC87072 antibody; NET32 antibody; SPFH 2 antibody; SPFH domain containing protein 2 antibody; SPFH domain family member 2 antibody; SPFH domain-containing protein 2 antibody; SPFH2 antibody; SPG18 antibody; Stomatin prohibitin flotillin HflC/K domain containing protein 2 antibody; Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2 antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1 (PubMed:19240031, PubMed:17502376). Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex (PubMed:21343306). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex (PubMed:24217618).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Erlin-2 protein (212-339AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:ERLIN2-Antibody-11909419.html
