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Antibodies

EIF2S3 Antibody

Product Sizes
50 ul
£186.00
CSB-PA007528ESR2HU-50UL
100 ul
£334.00
CSB-PA007528ESR2HU-100UL
About this Product
SKU:
CSB-PA007528ESR2HU
Additional Names:
eIF-2-gamma X antibody; eIF-2gA antibody; eIF-2gX antibody; EIF2 antibody; EIF2G antibody; EIF2gamma antibody; EIF2S3 antibody; Eukaryotic translation initiation factor 2 gamma antibody; Eukaryotic translation initiation factor 2 gamma subunit antibody; Eukaryotic translation initiation factor 2 subunit 3 antibody; Eukaryotic translation initiation factor 2 subunit 3 gamma 52kDa antibody; Eukaryotic translation initiation factor 2 subunit gamma X antibody; IF2G_HUMAN antibody
Application:
ELISA, Immunohistochemistry, Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
As a subunit of eukaryotic initiation factor 2 (eIF2), involved in the early steps of protein synthesis. In the presence of GTP, eIF2 forms a ternary complex with initiator tRNA Met-tRNAi and then recruits the 40S ribosomal complex, a step that determines the rate of protein translation. This step is followed by mRNA binding to form the 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF2 and release of an eIF2-GDP binary complex. In order for eIF2 to recycle and catalyze another round of initiation, the GDP bound to eIF2 must exchange with GTP by way of a reaction catalyzed by eIF2B (By similarity). Along with its paralog on chromosome Y, may contribute to spermatogenesis up to the round spermatid stage (By similarity).
Host:
Rabbit
Immunogen:
Recombinant Human Eukaryotic translation initiation factor 2 subunit 3 protein (173-472AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody