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Antibodies

EED Antibody

Product Sizes
50 ul
£186.00
CSB-PA007408ESR1HU-50UL
100 ul
£334.00
CSB-PA007408ESR1HU-100UL
About this Product
SKU:
CSB-PA007408ESR1HU
Additional Names:
eed antibody; EED protein antibody; EED; mouse; homolog of antibody; EED_HUMAN antibody; Embryonic ectoderm development antibody; Embryonic ectoderm development isoform a antibody; Embryonic ECTODERM development protein homolog antibody; Embryonic ectoderm development protein; mouse; homolog of antibody; hEED antibody; OTTHUMP00000235483 antibody; OTTHUMP00000235484 antibody; OTTHUMP00000235485 antibody; Polycomb protein eed antibody; WAIT 1 antibody; WAIT-1 antibody; WAIT1 antibody; WD protein associating with integrin cytoplasmic tails 1 antibody
Application:
ELISA, Immunohistochemistry, Western Blot
Buffer:
PBS
Clonality:
Polyclonal
Extra Details:
Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Also recognizes 'Lys-26' trimethylated histone H1 with the effect of inhibiting PRC2 complex methyltransferase activity on nucleosomal histone H3 'Lys-27', whereas H3 'Lys-27' recognition has the opposite effect, enabling the propagation of this repressive mark. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.
Host:
Rabbit
Immunogen:
Recombinant Human Polycomb protein EED protein (1-300AA)
Isotype:
IgG
Physical State:
Liquid
Purification:
Affinity Purified
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Supplier:
Cusabio
Type:
Antibody: Polyclonal Antibody