E2F6 Antibody
Product Sizes
50 ul
£186.00
CSB-PA007347ESR2HU-50UL
100 ul
£334.00
CSB-PA007347ESR2HU-100UL
About this Product
- SKU:
- CSB-PA007347ESR2HU
- Additional Names:
- E2F 6 antibody; E2F binding site modulating activity protein antibody; E2F transcription factor 6 antibody; E2F transcription factor 6 isoform 1 antibody; E2F-6 antibody; E2F6 antibody; E2F6_HUMAN antibody; EMA antibody; MGC111545 antibody; Transcription factor E2F6 antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. Overexpression delays the exit of cells from the S-phase.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Transcription factor E2F6 protein (1-281AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:E2F6-Antibody-11081819.html
