DDX5 Antibody
Product Sizes
50 ul
£186.00
CSB-PA006630ESR2HU-50UL
100 ul
£334.00
CSB-PA006630ESR2HU-100UL
About this Product
- SKU:
- CSB-PA006630ESR2HU
- Additional Names:
- ATP dependent RNA helicase DDX5 antibody; DDX 5 antibody; Ddx5 antibody; DDX5_HUMAN antibody; DEAD (Asp Glu Ala Asp) box helicase 5 antibody; DEAD (Asp Glu Ala Asp) box polypeptide 5 antibody; DEAD box 5 antibody; DEAD box protein 5 antibody; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 5 (RNA helicase; 68kD) antibody; G17P1 antibody; HELR antibody; HLR1 antibody; HUMP68 antibody; P68 antibody; p68 RNA helicase antibody; Probable ATP dependent RNA helicase DDX5 antibody; Probable ATP-dependent RNA helicase DDX5 antibody; RNA helicase p68 antibody
- Application:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre-mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for estrogen receptor ESR1 and androgen receptor AR. Increases ESR1 AF-1 domain-mediated transactivation and ESR1 AF-1 and AF-2 domains transcriptional synergistic activity. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 transcriptional activity and involved in skeletal muscle differentiation. Transcriptional coactivator for p53/TP53 and involved in p53/TP53 transcriptional response to DNA damage and p53/TP53-dependent apoptosis. Transcriptional coactivator for RUNX2 and involved in regulation of osteoblast differentiation. Acts as transcriptional repressor in a promoter-specicic manner; the function probbaly involves association with histone deacetylases, such as HDAC1. As component of a large PER complex is involved in the inhibition of 3' transcriptional termination of circadian target genes such as PER1 and NR1D1 and the control of the circadian rhythms.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Probable ATP-dependent RNA helicase DDX5 protein (1-290AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:DDX5-Antibody-11081995.html
