CBX4 Antibody
Product Sizes
50 ul
£186.00
CSB-PA004600ESR2HU-50UL
100 ul
£334.00
CSB-PA004600ESR2HU-100UL
About this Product
- SKU:
- CSB-PA004600ESR2HU
- Additional Names:
- CBX 4 antibody; CBX4 antibody; Cbx4 chromobox homolog 4 (Drosophila Pc class) antibody; CBX4_HUMAN antibody; Chromobox homolog 4 (Pc class homolog; Drosophila) antibody; Chromobox homolog 4 antibody; Chromobox protein homolog 4 antibody; E3 SUMO protein ligase CBX 4 antibody; E3 SUMO protein ligase CBX4 antibody; E3 SUMO-protein ligase CBX4 antibody; hPc 2 antibody; hPc2 antibody; NBP 16 antibody; NBP16 antibody; NS5ATP1 binding protein 16 antibody; Pc 2 antibody; Pc class 2 homolog antibody; Pc class homolog antibody; Pc class homolog Drosophila antibody; PC2 antibody; Polycomb 2 homolog antibody
- Application:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Clonality:
- Polyclonal
- Extra Details:
- E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human E3 SUMO-protein ligase CBX4 protein (401-560AA)
- Isotype:
- IgG
- Physical State:
- Liquid
- Purification:
- Affinity Purified
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Supplier:
- Cusabio
- Type:
- Antibody: Polyclonal Antibody
- Manufacturer's Data Sheet:CBX4-Antibody-1090930.html
